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Postdoctoral Scholars - Guldberg Lab

Apply now Job no: 529613
Work type: Faculty - Other
Location: Eugene, OR
Categories: Biology/Life Sciences, Natural Science, Research/Scientific/Grants, Human Physiology, Engineering/Biomedical Engineering

Department: Knight Campus
Rank: Postdoctoral Scholar
Annual Basis: 12 Month

Review of Applications Begins

June 13, 2022; open until filled

Special Instructions to Applicants

Along with your online application, please upload a cover letter and CV.

Department Summary

The Knight Campus for Accelerating Scientific Impact is a billion-dollar initiative designed to fast-track scientific discoveries and the process of turning those discoveries into innovations that improve the quality of life for people in Oregon, the nation, and beyond. The Knight Campus will reshape the higher education landscape in Oregon by training the next generations of scientists, forging tighter ties with industry and entrepreneurs, and creating new educational opportunities for graduate and undergraduate students.

Position Summary

The Postdoctoral Scholar will be responsible for conducting research and technical activities related to sponsored projects in Dr. Guldberg's lab. The incumbent will conduct data analysis on biometric and other data sets and collaborate on reporting findings and discoveries in written and verbal form; and will manage, maintain and provide technical expertise for Guldberg lab equipment, protocols, and programs in one of the following specialty areas.

Musculoskeletal Regenerative Rehabilitation – The objective of this program is to restore function to damaged musculoskeletal tissues through development of novel evidence-based treatments that combine regenerative therapies and physical rehabilitation protocols. For each project, coordinated 3D bioprinted patient-specific in vitro models, novel sensor-enabled preclinical models, instrumented rehabilitation systems, and predictive multivariate modeling techniques will be used to optimize functional recovery from injuries to bone, muscle, tendon/ligament, and cartilage. The Regenerative Rehabilitation program is part of the new $220 million Wu Tsai Human Performance Alliance.

Immunoengineering Strategies for Musculoskeletal Trauma - The goals of this NIH-funded project are to investigate (i) how the development of systemic immune dysregulation and immunosuppression relates to functional bone regeneration and (ii) how systemic immunomodulation impacts the immune system and regenerative outcomes following severe musculoskeletal trauma. This project combines established pre-clinical composite trauma models, systemic cellular and cytokine biomarkers of immune dysregulation, advanced machine learning algorithms, and nanoparticle-mediated immunomodulatory strategies to enhance functional regeneration following severe musculoskeletal injuries.

Post-Traumatic Osteoarthritis - The goals of this research are to develop early interventions for joint trauma that accelerate healing and reduce or even prevent downstream post-traumatic osteoarthritis. We are developing joint-specific, patient-specific in vitro model systems as well as in vivo preclinical injury models and using these to perform high throughput therapeutic testing. Other work involves identifying early biomarkers and cell signaling pathways that predict osteoarthritis to formulate candidate therapies and delivery vehicles that specifically target affected joint tissues. We are also exploring combination treatments that would synergize exercise, intra-articular injectables, and modulated movement biomechanics to reduce pain, pathologic locomotion, and degenerative structural joint conditions. This research is supported by the Wu Tsai Human Performance Alliance.

Minimum Requirements

• Ph.D in Mechanical or Biomedical Engineering, Human Physiology, Immunology, or other relevant field
• One year of laboratory experience in regenerative medicine, biomarker assays, and preclinical models

Professional Competencies

• Demonstrated strong written and oral communication skills

Preferred Qualifications

• Strong academic record
• Bioprinting and cell culture experience
• Biomaterials expertise
• Experience with biomechanical testing and modeling
• Experience with multivariate modeling and/or machine learning algorithms

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The University of Oregon is proud to offer a robust benefits package to eligible employees, including health insurance, retirement plans and paid time off. For more information about benefits, visit http://hr.uoregon.edu/careers/about-benefits.

The University of Oregon is an equal opportunity, affirmative action institution committed to cultural diversity and compliance with the ADA. The University encourages all qualified individuals to apply, and does not discriminate on the basis of any protected status, including veteran and disability status. The University is committed to providing reasonable accommodations to applicants and employees with disabilities. To request an accommodation in connection with the application process, please contact us at uocareers@uoregon.edu or 541-346-5112.

UO prohibits discrimination on the basis of race, color, sex, national or ethnic origin, age, religion, marital status, disability, veteran status, sexual orientation, gender identity, and gender expression in all programs, activities and employment practices as required by Title IX, other applicable laws, and policies. Retaliation is prohibited by UO policy. Questions may be referred to the Title IX Coordinator, Office of Civil Rights Compliance, or to the Office for Civil Rights. Contact information, related policies, and complaint procedures are listed on the statement of non-discrimination.

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